Specialty / Emerging

Klotho

Research / preclinical

Longevity hormone — declining levels correlate with age-related decline.

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Mechanism

Longevity hormone. Longevity hormone — declining levels correlate with age-related decline. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.

Peer-Reviewed Studies (2)

Klotho Mutation Causes Aging-Like Phenotype

Nature · 1997

Discovery: Klotho deficiency produces premature aging in mice.

PubMed PMID 9363890 →

Klotho and Cognition in Humans

Cell Reports · 2014

Higher Klotho variant associated with better cognition.

PubMed PMID 24816400 →

Related Compounds

GDF-11

Anti-aging factor — controversial young-blood research.

Follistatin (FST-344)

Myostatin inhibitor — muscle growth research, gene therapy parallels.

Lithium Orotate (low-dose)

Microdose lithium — mood, longevity epidemiology in tap water studies.

Ostarine (MK-2866)

Selective androgen receptor modulator — most-studied SARM. Research only, not approved.

LGD-4033 (Ligandrol)

AR modulator — bone and muscle research. Research compound, not approved for human use.