Levothyroxine
FDA approvedAlso known as: Synthroid, Levoxyl, Tirosint
The most-prescribed drug in America — synthetic T4 for hypothyroidism.
Mechanism
Thyroid hormone (T4). The most-prescribed drug in America — synthetic T4 for hypothyroidism. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.
Peer-Reviewed Studies (2)
ATA Guidelines for Hypothyroidism Treatment
Authoritative guidelines establishing levothyroxine as first-line.
PubMed PMID 25266247 →Combination T4 + T3 vs T4 Monotherapy
Subset benefits from combination therapy or NDT.
PubMed PMID 29547180 →