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Home / Compounds / GH Secretagogues

GH Secretagogues

7 compounds · 15 peer-reviewed studies

Tesamorelin

FDA

FDA-approved GHRH analog with the strongest visceral fat reduction data.

Sermorelin

Tier 2

First-generation GHRH analog — short half-life produces clean, physiological GH pulses.

CJC-1295 (with DAC)

Tier 2

Long-acting GHRH analog — DAC modification extends half-life to 6+ days.

Mod GRF 1-29 (CJC-1295 no DAC)

Tier 2

The pulsatile cousin of CJC-1295 — short half-life, clean pulses, ideal stack with ipamorelin.

Ipamorelin

Tier 2

The cleanest GHRP — selective GH release with no significant cortisol or prolactin elevation.

GHRP-2

Tier 2

Stronger GH release than ipamorelin, with cortisol and appetite trade-offs.

MK-677 (Ibutamoren)

Tier 2

The only orally bioavailable GH secretagogue — sustained GH/IGF-1 elevation in pill form.

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