GH Secretagogues

Sermorelin

Compounding-legal

Also known as: Geref

First-generation GHRH analog — short half-life produces clean, physiological GH pulses.

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Mechanism

GHRH analog. First-generation GHRH analog — short half-life produces clean, physiological GH pulses. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.

Peer-Reviewed Studies (2)

GHRH Analogs and Endogenous GH Pulsatility

JCEM · 2009

GHRH analogs increase GH pulse amplitude without disrupting normal patterns.

PubMed PMID 19276237 →

Sermorelin in Adult Growth Hormone Deficiency

Endocr Pract · 2014

Improved IGF-1 levels and quality of life in adults with GHD.

PubMed PMID 24793923 →

Related Compounds

Tesamorelin

FDA-approved GHRH analog with the strongest visceral fat reduction data.

CJC-1295 (with DAC)

Long-acting GHRH analog — DAC modification extends half-life to 6+ days.

Mod GRF 1-29 (CJC-1295 no DAC)

The pulsatile cousin of CJC-1295 — short half-life, clean pulses, ideal stack with ipamorelin.

Ipamorelin

The cleanest GHRP — selective GH release with no significant cortisol or prolactin elevation.

GHRP-2

Stronger GH release than ipamorelin, with cortisol and appetite trade-offs.

MK-677 (Ibutamoren)

The only orally bioavailable GH secretagogue — sustained GH/IGF-1 elevation in pill form.