Senolytics

FOXO4-DRI

Research / preclinical

Peptide senolytic — disrupts FOXO4-p53 interaction in senescent cells.

Mechanism

Peptide senolytic. Peptide senolytic — disrupts FOXO4-p53 interaction in senescent cells. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.

Peer-Reviewed Studies (2)

Targeted Apoptosis of Senescent Cells (FOXO4-DRI)

Cell · 2017

Original discovery: peptide selectively eliminated senescent cells.

PubMed PMID 28340339

FOXO4 in Senescence Signaling

Aging Cell · 2019

Reviewed FOXO4 mechanism and therapeutic targeting.

PubMed PMID 30773784

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