Senolytics

Spermidine

Research / preclinical

Polyamine — induces autophagy, found in wheat germ and aged cheese.

Mechanism

Polyamine autophagy inducer. Polyamine — induces autophagy, found in wheat germ and aged cheese. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.

Peer-Reviewed Studies (2)

Cardioprotection and Lifespan Extension by Spermidine

Nat Med · 2016

Spermidine extended lifespan and cardioprotected aged mice.

PubMed PMID 27841876

Spermidine in Memory Performance Older Adults

Cortex · 2018

Improved memory in older adults at risk for dementia.

PubMed PMID 29982075

Related Compounds