MOTS-c
Compounding-legalAn exercise mimetic encoded by mitochondrial DNA — activates AMPK signaling.
Mechanism
Mitochondrial-derived peptide. An exercise mimetic encoded by mitochondrial DNA — activates AMPK signaling. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.
Peer-Reviewed Studies (3)
MOTS-c Promotes Metabolic Homeostasis
Discovery: AMPK activation, prevented diet-induced insulin resistance.
PubMed PMID 25738459 →MOTS-c is Exercise-Induced Mitochondrial-Encoded Regulator
Improved physical performance in aged mice; exercise raises endogenous levels.
PubMed PMID 33479211 →MOTS-c and Cellular Energetics
Enhanced exercise capacity and glucose tolerance.
PubMed PMID 30735833 →