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Home / Compounds / Longevity Polyphenols

Longevity Polyphenols

8 compounds · 16 peer-reviewed studies

Resveratrol

Tier 3

SIRT1 activator — Sinclair lab classic, mechanism well-studied.

Pterostilbene

Tier 3

Resveratrol analog with better bioavailability — same SIRT1 pathway, longer half-life.

Quercetin

Tier 3

Flavonoid — senolytic component (D+Q stack), anti-inflammatory, mast cell stabilizer.

Apigenin

Tier 3

Flavone CD38 inhibitor — boosts NAD+ via different pathway than NMN/NR.

Curcumin (Meriva)

Tier 3

Anti-inflammatory polyphenol — Meriva/Theracurmin formulations for bioavailability.

EGCG

Tier 3

Green tea catechin — antioxidant, mild metabolic effects, take with food.

Sulforaphane

Tier 3

Nrf2 activator from broccoli sprouts — phase 2 detox, antioxidant defense.

Astaxanthin

Tier 3

Carotenoid antioxidant — strong antioxidant capacity, skin photoprotection, eye health.

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