Longevity Polyphenols

EGCG

Research / preclinical

Green tea catechin — antioxidant, mild metabolic effects, take with food.

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Mechanism

Green tea catechin. Green tea catechin — antioxidant, mild metabolic effects, take with food. For full mechanism, dosing protocol, and stacking guidance, ask the AI Advisor or open the compound in-app.

Peer-Reviewed Studies (2)

EGCG Effects on Cardiovascular Risk Factors

Am J Clin Nutr · 2008

Improved lipid profile and blood pressure in human studies.

PubMed PMID 18065582 →

EGCG Hepatotoxicity Risk Review

Toxicol Lett · 2018

Reviewed dose-dependent hepatotoxicity at high concentrations.

PubMed PMID 29870796 →

Related Compounds

Resveratrol

SIRT1 activator — Sinclair lab classic, mechanism well-studied.

Pterostilbene

Resveratrol analog with better bioavailability — same SIRT1 pathway, longer half-life.

Quercetin

Flavonoid — senolytic component (D+Q stack), anti-inflammatory, mast cell stabilizer.

Apigenin

Flavone CD38 inhibitor — boosts NAD+ via different pathway than NMN/NR.

Curcumin (Meriva)

Anti-inflammatory polyphenol — Meriva/Theracurmin formulations for bioavailability.

Sulforaphane

Nrf2 activator from broccoli sprouts — phase 2 detox, antioxidant defense.